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Vitamin B12 may play a role in fertility by supporting proper hormone balance and reproductive health." Agyeman also says that vitamin B12 is involved in bone metabolism and mineralization, so having adequate levels of B12 is especially important for women as they are more prone to bone disorders like osteoporosis

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The majority of newly diagnosed children by NBS is asymptomatic or mildly affected because of relative high residual enzyme activity [22, 60, 121]

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